Skin Concerns

Best Anti-Aging Night Creams

Here are experts' favourite best anti-aging night creams for reducing worry lines, fighting wrinkles, and evening skin tone.
By Dermspotlight Staff,
Updated Nov 22, 2022
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Aging is a natural part of life, but it can also have an impact on your skin. Your skin might start to look dry, wrinkly, and saggy. Aging is unavoidable, but there are things you can do to slow down the process.

The first thing you should do is use a night cream. Night creams are designed specifically for nighttime use because they contain ingredients that work during sleep hours, which is when your body repairs itself and regenerates new cells.

Night creams can help reduce wrinkles and fine lines while also improving the firmness and elasticity of the skin. They also help decrease dark spots caused by sun exposure, which makes them perfect for people with oily or acne-prone skin types who tend to break out in acne during their teenage years and early adulthood.

best night creams for anti-aging
Anti-aging night creams can help refining the skin tone, reducing the appearance of fine lines and wrinkles. Image/Dermspotlight
If you’re looking for the best night cream, there are a few things to consider. First, you must determine your skin type. Is it dry? Oily? Normal? The next step is to look at the active ingredients in your night cream. What does it contain? Does it have any irritants or allergens in it? Finally, you need to find a night cream that matches your budget and expectations.

These days there are so many different night creams available that it can be hard to find one that works best for you, especially if you have specific needs such as under your eyes. You can start by narrowing down your options based on what kind of skin type you have: oily, dry, or normal. Then look at the ingredients in each product and make sure they won’t irritate your skin or cause an allergic reaction (if they do then discontinue use immediately).

If you’re like us, you’ve spent countless hours trying to figure out which moisturizing cream works. We’ve all been there—we know how frustrating it can be to try and find the right product for your skin.

Our mission is to make it easier for everyone to have healthy skin by providing only the best products that are safe and effective.

We’ve put hundreds of brands through rigorous testing and have narrowed down our list of favorites based on their ability to deliver results in a short amount of time.

Benefits of Anti-Aging Night Creams

Anti-aging night creams are a great way to ensure that you’re getting the benefits of a cream without having to deal with any of the harsh chemicals or fragrances that may be found in other, cheaper options.

Night creams are typically recommended for people who are looking for a heavy-duty moisturizer that will help them keep their skin looking young and healthy. This can involve things like reducing wrinkles and fine lines, as well as helping to keep your skin hydrated and preventing it from becoming too dry or flaky.

The main benefit of using anti-aging night creams is that they are designed to work overnight when your skin’s natural regeneration process is at its most active. This means that you will start seeing results much faster than with other types of cream. [1]

It may surprise you to know that those who don’t sleep well may experience signs of aging quicker than those who get 6-8 hours of sleep at night. This is because without sleep your body can not produce collagen which is a protein that helps your skin stay firm and increases elasticity. [2]

Our Top Night Cream Picks

DRMTLGY Peptide Night Cream

Drmtlgy Peptide Night Cream

Drmtlgy’s Peptide Night Cream is great for all skin types, including sensitive skin. It nourishes and hydrates the skin as you sleep, and it also tightens and firms to smooth fine lines and wrinkles. According to the manufacturer, the night cream uses 100% safe, organic ingredients, with no parabens, sulfates, fragrances, or other additives or agents that could cause a skin reaction.

  • Price: $46

Container Type: Jar | Skin Type: For All Skin Types | Size: 2 fl oz (15 ml) | Form: Cream | Brand: Drmtlgy

Active Ingredients
Shea Butter is high in anti-inflammatory and antioxidant properties, and it can repair, protect, and help heal wounds and skin conditions.

Peptides are amino acid chains that are used to make proteins such as collagen and elastin. It hydrates the skin, boosts immunity, and aids in skin protection and repair.

Ceramides aid in the removal of dry, dull, flaky skin. It is highly hydrating and forms a protective film that prevents bacteria and other harmful agents from entering.

RoC Retinol Correxion Night Cream

RoC Retinol Correxion Night Cream

RoC is a popular anti-aging night cream that is highly effective at reversing some signs of aging, including fine lines around the eyes and minimizing dark spots. The key ingredients are Hyaluronic Acid and caffeine.

  • Price: $113

Container Type: Jar, Pump Bottle | Skin Type: For All Skin Types | Size: 1 fl oz (30 ml) | Form: Cream | Brand: RoC

Olay Regenerist 24 Night Recovery Cream

Olay Regenerist 24 Night Recovery Cream

This fragrance-free night cream helps to even out skin tone and works great for sensitive skin. It helps to reduce the appearance of fine lines on the forehead and hydrates the skin. The main ingredients in this product are Vitamin B, e, and olive oil extract.

  • Price: $24.99

Container Type: Jar | Skin Type: For All Skin Types | Size: 1.7 fl oz | Form: Cream | Brand: Olay

Neutrogena Rapid Wrinkle Repair

Neutrogena Rapid Wrinkle Repair

This budget-friendly night moisturizer helps rapidly improve wrinkles and does not make a dent in your wallet. This wrinkle night cream helps to reduce fine lines, wrinkles, and dark spots along with hydrating your skin. The main ingredients are Hyaluronic acid and retinol.

  • Price: $26.23

Container Type: Jar | Skin Type: For All Skin Types | Size: 1.7 fl oz | Form: Cream | Brand: Neutrogena

Formulyst Anti-Aging Night Cream

Formulyst Anti-Aging Night Cream

Formulyst Anti-Aging Night Cream is an anti-aging cream that is designed to help you achieve a younger-looking, more youthful appearance. Formulyst Anti-Aging Night Cream is made with several ingredients, including hyaluronic acid, which helps to moisturize and hydrate the skin.

  • Price: $59.00

Container Type: Bottle | Skin Type: For All Skin Types | Size: 1 fl oz | Form: Cream | Brand: Formulyst

Algenist GENIUS Ultimate Anti-Aging Cream

Algenist GENIUS Ultimate Anti-Aging Cream

The Algenist GENIUS Ultimate Anti-Aging Cream is a product that helps to reverse the signs of aging. It provides gentle exfoliation and improves skin texture, tone, and firmness. The anti-aging cream also helps to improve the appearance of fine lines, wrinkles, and pores.

  • Price: $112

Container Type: Jar | Skin Type: For All Skin Types | Size: 2 fl oz | Form: Cream | Brand: Algenist

Drunk Elephant A-Passioni Retinol Cream

Drunk Elephant A-Passioni Retinol Cream

Drunk Elephant A-Passioni Retinol Cream is one of the best anti aging eye cream that helps you to look and feel younger. It penetrates deep into your skin to erase fine lines and wrinkles while increasing the elasticity of your skin and improving its firmness.

  • The Reviewers Say: Most of the reviewers loved this eye cream and said it was a powerful wrinkle remover.
  • Price: $74.00

Container Type: Pump Bottle | Skin Type: For All Skin Types | Size: 1 fl oz | Form: Cream | Brand: Drunk Elephant

SkinCeuticals A.G.E. Interrupter

SkinCeuticals A.G.E. Interrupter

SkinCeuticals A.G.E. Interrupter is a daily moisturizing pad that helps fight the signs of aging by reducing the appearance of wrinkles and age spots. The unique formula contains tranexamic acid, an active ingredient that has been shown to help reduce the appearance of wrinkles and discoloration while improving skin hydration and elasticity.

  • Price: $168.00

Container Type: Jar | Skin Type: For All Skin Types | Size: 1.7 fl oz | Form: Cream | Brand: SkinCeuticals

Murad Retinol Youth Renewal Serum

Olay Regenerist Eye Lifting Serum

Retinol Youth Renewal Serum by Murad is a product that promises to reduce the signs of aging, including wrinkles and fine lines. This product contains vitamin A, which is responsible for promoting cell renewal, reducing fine lines and wrinkles, and improving overall skin texture. Retinol also promotes collagen production, improving skin elasticity and reducing sagging or loose skin.

  • Price: $25.12

Container Type: Bottle, Tube | Skin Type: Balanced, Pily, Combination, Dry, Normal | Size: 1 fl oz | Form: Serum | Brand: Murad

StriVectin Advanced Retinol Intensive Night Moisturizer

StriVectin Advanced Retinol Intensive Night Moisturizer

StriVectin Advanced Retinol Intensive Night Moisturizer is a night cream that contains retinol, an ingredient known to promote collagen production and skin cell turnover. This helps to boost your skin’s natural repair process as you sleep, so you wake up with a fresh, healthy look.

  • Price: $85.99

Container Type: Tube | Skin Type: For All Skin Types | Size: 1.7 fl oz | Form: Cream | Brand: StriVectin

What To Look For In Best Anti-aging Night Creams

When looking for a best night cream, there are several factors to consider.

First, you should consider the ingredients in the night cream. If you have sensitive skin or an allergy to any of the ingredients listed on the bottle, it’s best to avoid that product. The same goes for skin concerns—if you’re looking for a product that will help your skin retain moisture and reduce fine lines and wrinkles but it contains ingredients like salicylic acid or retinol, you might want to look elsewhere.

You should also take into account the reputation of the company selling the product. If they don’t have a good track record of customer service or customer satisfaction, then it’s probably not worth purchasing from them. It’s also important to check whether or not they offer any guarantees on their products—this can give you some peace of mind if something goes wrong with your purchase.

Finally, it’s important to consider cost when shopping around for night creams—after all, some companies charge more money than others! However, this isn’t necessarily indicative of quality; just make sure that you’re getting what you pay for before committing yourself financially to a certain brand or product line!

Ingredients You Need To Look for In Night Creams for Aging

If you’re looking for an anti-aging night cream, it’s important to know what ingredients are in the product that you’re considering purchasing.

Here are some of the most common anti-aging ingredients:

Vitamin C

This potent antioxidant can help protect skin from environmental stressors, including pollution and sun exposure. [3]


This form of vitamin A is often used in anti-aging products because it stimulates cell turnover, which helps remove dead skin cells and reveal new, healthy ones.[4]

Hyaluronic Acid

This ingredient can boost hydration levels by attracting water molecules to cells and improving their ability to retain moisture.[5]

Vitamin E

It is another powerful antioxidant that works to protect your skin from UV rays and other environmental factors that can cause damage. It also helps repair damaged skin cells.[6]

Ferulic Acid

It is one of the best natural antioxidants available on the market today. It has been shown to increase collagen production by up to 70%, which helps reduce wrinkles and dark spots on your face.[7]

Sodium Hyaluronate

It is a popular ingredient in night creams because it helps to attract and retain water. This helps to hydrate the skin, which can be especially helpful if you have dry or dehydrated skin.[8]

Alpha- and beta-hydroxy acids

Work by exfoliating the skin, removing dead skin cells and encouraging new cell growth. Glycerin is another ingredient that helps to keep moisture in the skin, while lactic acid works by stimulating collagen production and helping to brighten the complexion.[9]


Glycerin is a humectant that attracts water from its environment into your skin cells, making them plump up with moisture and smooth out any wrinkles or fine lines they may have developed over time through exposure to sun damage or other environmental factors like pollution or cigarette smoke (which we all know is bad for your health).[10]

Lactic Acid

It is a naturally-occurring alpha hydroxy acid that works to exfoliate and brighten skin when applied topically. It’s also known for its ability to soften and smooth the appearance of fine lines and wrinkles, as well as improve the appearance of acne scars.[11]

Anti-Aging Creams: The Reality

While anti-aging night creams help reverse many of the signs of aging, they aren’t able to change the most significant case of aging, which is your DNA and other contributing factors such as oxidative stress, glycation, and fluctuating hormones. However, there are some signs of aging we can control, such as smoking, poor sleep habits, our diets, excessive alcohol use, and sun exposure. Additional influences on aging:


Studies have shown that smoking causes premature wrinkling. While the exact reasons for this are not fully understood, it is believed that when you smoke, you inhale toxins that can damage your skin cells and cause them to age faster.

Sleeping habits

People who sleep too little or too much tend to age faster than those who get an adequate amount of sleep each night.

Daily facial movements

Smiling and frowning help maintain youthful skin by keeping blood flowing to the surface of your face, where it provides oxygen and nutrients to keep your skin healthy.

Weight changes

If you gain or lose weight without exercising regularly, it can affect the appearance of your face—particularly around your mouth area—and make you look older than you really are. Weight changes can also cause other physical ailments caused by age, like joint pain or arthritis.


For example, gravity causes our skin to sag because it pulls on our faces as we age. Gravity also makes our joints stiffer and less flexible as we get older, which can make it difficult to do everyday activities.


Q: Are night creams or moisturizers better?

A: To wear while you’re sleeping, night creams are better because they are formulated with specific ingredients that work with your skin during the reparative process.

Q: When should I start using anti-aging night creams?

A: We recommend starting using a night cream for aging skin when you are in your 20s.

Q: Can I use a night cream every night?

A: Yes, you can use night cream nightly.

Q: Do night creams really work?

A: Yes, hydrating night creams help prevent the loss of water while you’re sleeping because they are thicker than day creams and formulated with specific ingredients that hydrate and repair your skin.

The Bottom Line

Our top pick for an anti-aging moisturizer is Drmtlgy Peptide Night Cream because of it’s affordable price and outstanding results.

Remember, when using a skincare regime, you can’t totally reverse the signs of aging because there’s no such thing as a miracle cream. However, you can help your skin while it’s in a reparative state work a bit better by applying an anti-aging night cream.

Joanna McGetrick, MD, FAAD

By Joanna McGetrick, MD, FAAD

Dr. Joanna McGetrick, MD is a Dermatologist in Orlando, Florida. She is board certified by the American Board of Dermatology. She focuses on a combination of complex medical dermatology, surgical procedures, and cosmetic dermatology.

11 sources

[1] National Library of Medicine, the Journal of Clinical and Aesthetic Dermatology Circadian Rhythm and the Skin: A Review of the Literature published September 1, 2019.
[2] National Library of Medicine Does poor quality affect skin aging? Published January 2015.
[3] Al-Niaimi F, Chiang NYZ. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. J Clin Aesthet Dermatol. 2017 Jul;10(7):14-17. Epub 2017 Jul 1. PMID: 29104718; PMCID: PMC5605218.
[4] Harvard Health Publishing Harvard Medical School Published March 3, 2022
[5] National Library of Medicine Dermato Endocrinology Hyaluronic acid: A key molecule in skin aging published July 1, 2012
[6] Healthessentials Vitamin E for skin: What Does It Do? Published February 24, 2022
[7] MedicalNewsToday What do know about ferulic acid published March 30, 2022
[8] MedicalNewsToday Sodium hyaluronate in skin care: What to know published March 29, 2022
[9] Tang SC, Yang JH. Dual Effects of Alpha-Hydroxy Acids on the Skin. Molecules. 2018 Apr 10;23(4):863. doi: 10.3390/molecules23040863. PMID: 29642579; PMCID: PMC6017965.
[10] Safety Assessment of Glycerin as Used in Cosmetics
[11] Medical NewsToday Uses and benefits of lactic acid in skin care published March 30, 2022