What is Introstem Skincare?

Introstem skincare is a beauty brand that uses grape stem cell extracts alongside scientifically backed ingredients rich in humectants and antioxidants to resolve specific skin concerns. Most of their bestselling products are anti-aging solutions. For instance, the brand’s Hydrolift collection is a line of specialized anti-aging products carefully formulated to reduce the appearance of wrinkles and fine lines on the face and neck.

Hydrolift transforming mask, as its name suggests, claims to transform tired old skin into a supple and hydrated one. The Hydrolift stem cell drops claim to promote a healthier and brighter complexion. In contrast, the Hydrolift face and neckline cream claims to have supercharged vitamins and peptides to improve skin elasticity and rejuvenation.

Introstem Skincare Review
Introstem Skincare Review. Image/Dermspotlight

Fast Facts

Introstem Skincare

Types: All skin types
Uses: hydrating the skin, treating aging symptoms
Active Ingredients: Hemp seed oil, grape stem extract, retinyl palmitate, essential fatty acids, shea butter, vitamin A, vitamin C
Price: $120 – $2400
About the Brand: Introstem Skincare is a luxury brand that uses hemp seed oil and grape stem cells to treat skin problems.

Best Selling Introstem Products

1. Hydrolift Age Reforming Alpha Solution

Reduces fine lines and reverses aging symptoms.

What It Does: This solution is effective in minimizing the appearance of wrinkles and fine lines around the mouth, nose and eyes area through antioxidant rich ingredients such as Alpha Hydroxy Acids. It’ll leave your skin feeling plumper and younger.

Key Ingredients: Vitamin A, avocado oil, grape seed extract, squalane, sodium hyaluronate, vitamin E


*All individuals are unique. Your results can and will vary.

Price: $1950

2. Introstem Hydrolift Face and Neck Cream

Makes loose skin firmer.

What It Does: This cream is loaded with anti-aging peptides and vitamins that work to tighten, tone, and improve the skin. It has a pleasant smell and a wonderfully rich, creamy consistency that the skin can easily absorb.

Key Ingredients: Vitamin A, green teas leaf extract, jojoba seed oil, safflower seed, grape seed extract, vitamin E

Price: $1200

3. Introstem Stem Cell Day Moisturizer

Hydrates the skin.


*All individuals are unique. Your results can and will vary.

What It Does: This cream is a combination of Shea Butter, Grape Stem Cells and Vitamin E. It’s formulated to keep the skin soft and supple while also shielding it from the elements. Applying the Stem Cell Day Moisturizer on a regular basis will give your skin a more youthful appearance and feel.

Key Ingredients: Vitamin E, grape stem cells, shea butter, glycerin, safflower seed oil, vitamin A, hemp seed oil.

Price: $350

Is Introstem any Good?

Introstem skincare contains a lot of beneficial substances such as omega-6 and omega-3 fatty acids as well as minerals such as magnesium and potassium. In addition, the products stem cells are supposed to provide antioxidant protection, reduce irritation and inflammation and leave skin looking supple and smooth.

Their list of ingredients is not something to laugh at either. Introstem combines potent vitamins, peptides, antioxidants, minerals, and humectants to restore life and radiance to the skin. It features grape stem cell extract, which, when applied to the skin, transforms into living cells and promotes skin regeneration and healing.

How Does Introstem Work?

Introstem skincare works through its ingredients which are designed to combat the signs of aging, so they don’t appear as pronounced as they once were. The most common ingredient is grape seed cell extract, which as discussed in our ReActivate reviews, has multiple skin related benefits.

The epidermis’s basal layer is home to the bulk of the body’s stem cells. The skin needs them the most during the homeostasis and wound-healing processes of homeostasis, where they serve as a regenerative boost. Knowing how stem cells function in the skin is essential before purchasing a product containing stem cells.

Even though the skin regularly regenerates itself throughout adulthood, the stem cells responsible for this renewal become less efficient at producing new cells as we age. It’s believed that a decrease in the number of stem cells or their capacity to respond to regenerative signals are potential causes of the slower tissue repair rate in aging skin.

Recently, researchers have discovered that natural botanicals with high antioxidant activities can protect skin stem cells against ultraviolet oxidative stress, regulate swelling, eliminate free radicals, and treat the signs of photoaging. Because of this, skincare ingredients with plant stem extracts have been recognized as having the capacity to encourage healthy cell growth and guard against cellular damage from sun rays.

All products, including the Introstem Night Moisturiser, have stem cells as part of their main ingredients.


*All individuals are unique. Your results can and will vary.

What Are the Ingredients in Introstem

Some of the significant ingredients in the Introstem skincare line are:

Grapefruit stem cell extract

Skincare companies specifically choose ultraviolet light-resistant grapes for the purpose of extracting their stem cell. They can fortify adult stem cells in the skin against any damage, keep them healthy, and even spur their regeneration. They contain polyphenolic substances such as proanthocyanidins, anthocyanins, and antioxidants.

Anthocyanins reduce inflammation and protect cells from free radical damage. [1] Proanthocyanidins have antioxidant properties and also work to strengthen collagen, preserve elastin, minimize edema, and retain skin elasticity.

Vitamin E

Tocopherol, or vitamin E, is a substance commonly seen in cosmetics products. It’s a natural antioxidant that helps to defend the skin from harmful free radicals.

Free radicals are particles that are present in the environment and are responsible for causing damage to your skin and reducing its suppleness. Some of their sources are chemicals, the sun, pollution, and cigarette smoke and because they’re so common, avoiding them is futile. [2] But vitamin E is like an invisible armor that protects your skin from all the environmental hazards it faces daily. [3]

Furthermore, Vitamin E is a fat-soluble substance, which means your skin can easily absorb it to protect the lipids (fats) in your body while repairing your skin’s protective barrier. It also takes care of inflammation and soothes the skin. [4]

Hemp Seed Oil

Hemp seed oil, sometimes known as hemp oil, is a popular treatment in skincare. According to studies, hemp oil’s high omega-3 and omega-6 content have shown promise as a treatment for various skin disorders as referenced in our Truly Beauty review article. Some claim that it can reduce inflation and serve as a folk remedy for cancer.

Hemp oil, according to a 2014 study, is a powerful anti-acne treatment. According to the research, further clinical trials are required to determine the most effective applications.

Staphylococcus aureus was one of many species of bacteria found to be suppressed by hemp oil’s antibacterial properties in a study conducted in 2017. Infections caused by Staphylococcus aureus are severe and can spread to other parts of the body, including the skin, lungs, bones, and heart valves.

Introstem Reviews

Introstem has overwhelmingly positive reviews. You can find some of them on the brand’s official website. The website has three hundred and seventeen reviews that cut across all products. Many customers have mentioned the moisturizing quality of the products and how it wouldn’t be farfetched to label them as miraculous creams. The most common review by past customers is that the products do exactly what they claim to do and

Introstem Skincare Alternatives

Brand: Skinception Eyelasticity

Price: $59.95

Ingredients: Syn®-ake, Beta Glucan, Grape Seed Oil

Introstem Skincare Refund Policy

Introstem does not offer refunds. However, it allows people to make exchanges within 30 days if they’re not satisfied with their initial products. So, make sure you make an exchange within that time frame if you don’t like any product you buy.

How Much Do Introstem Skincare Products Cost?

Introstem skincare costs somewhere between $120 to $2400 individually. The brand offers free shipping in the U.S., some giveaway, and a 20% discount when you sign up and subscribe to the brand’s newsletter for the first time. These freebies are available at the moment, but we don’t know whether they’ll be in the future.

Introstem Skincare FAQs

Q: Has the FDA approved Introstem?

A: The FDA has approved Introstem. Although skincare products are exempt from FDA approval, this additional level of confidence demonstrates that it doesn’t include any potentially dangerous components.

Q: Is Introstem Safe?

A: You shouldn’t even consider taking Introstem if you react to any of its ingredients. Using a product without first performing a patch test can damage the skin. However, Introstem certifies that its goods are safe to use; after completing a test run and it suits your skin, you may start to use it.

Q: What negative impacts does Introstem have on the skin?

A: People who want to use Introstem skincare products should exercise caution because, according to reviews, they may not be suitable for persons with allergies. Before using this brand, consult your dermatologist.

Q: How should you use Introstem products?

A: It’s best to consult the label for application directions as the methods for applying different Introstem products differ.

Final Thoughts

Everyone who cares about their skin and how their face and neck look and has the means to treat themselves should consider purchasing Introstem.

Thanks to their website’s organized list of skin problems, you can quickly find what you need. Check out their Stem Cell Vitamin C Serum if you’re concerned about aging and sun spots. They have a stem cell serum and a firming eye lotion for tired eyes.

If you’re worried about skin dryness, you should look into trying out their Stem Cell Day Moisturizer and Night Repair. You won’t regret giving these a try if you’re serious about providing your skincare routine a boost. However, if your budget is limited, you might consider getting other similar products.

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4 Sources

[1] Goutzourelas, N., Stagos, D., Spanidis, Y., Liosi, M., Apostolou, A., Priftis, A., Haroutounian, S., Spandidos, D. A., Tsatsakis, A. M., & Kouretas, D. (2015). Polyphenolic composition of grape stem extracts affects antioxidant antioxidant activity in endothelial and muscle cells. Molecular medicine reports, 12(4), 5846–5856. https://doi.org/10.3892/mmr.2015.4216
[2] Keen, M. A., & Hassan, I. (2016). Vitamin E in dermatology. Indian dermatology online journal, 7(4), 311–315. https://doi.org/10.4103/2229-5178.185494
[3] Nachbar, F., & Korting, H. C. (1995). The role of vitamin E in normal and damaged skin. Journal of molecular medicine (Berlin, Germany), 73(1), 7–17. https://doi.org/10.1007/BF00203614
[4] Liu, X., Yang, G., Luo, M., Lan, Q., Shi, X., Deng, H., Wang, N., Xu, X., & Zhang, C. (2021). Serum vitamin E levels and chronic inflammatory skin diseases: A systematic review and meta-analysis. PloS one, 16(12), e0261259. https://doi.org/10.1371/journal.pone.0261259