What is ZO Skin Health?

ZO Skin Health is skincare line that was founded by the world’s renowned dermatologist Dr. Zein Obagi.

Dr. Obagi is also the founder of Obagi Skincare, a brand available from Walmart to TheDermStore.com. In 2006, Dr. Obagi left Obagi Skincare, and in 2007, he launched a new skincare brand called ZO Skincare.

Fast Facts

ZO Skin Health

About the Brand: Founded in 2007 by Dr. Zein Obagi, available on major retailer sites, dermatology recommended, GMP compliant.
Top Selling Products: Daily Power Defense, Oil Control Pads, Exfoliating Polish, Growth Factor Serum, Exfoliating Cleanser, Vitamin C Self Activating, Retinol Skin Brightener
Best for: Skin exfoliation, oiling dry skin, collagen boosting, wrinkle reduction, dark spots, loose skin, dull skin
Key Ingredients: Vitamin C, Glycolic acid, Retinol, Salicyic acid.
Price Range: $30 – $150+
ZO Skin Health
ZO Skin Health. Image/Dermspotlight

What Are the Best Selling ZO Skin Health Skin Care Products?

ZO Skin Health Exfoliating Polish

The exfoliating polish helps get rid of dead skin cells and helps revive dull, tired skin. The formula contains magnesium oxide crystals that exfoliate the skin and give you a smooth and even complexion. The formula also contains bicarbonate soda, which may be a harsh exfoliator for the skin.

The brand claims that Vitamin C is a key ingredient in the exfoliator. However, the PH of the product should be less than 3.5 for vitamin C to be absorbed.

The product also contains fragrances that may cause skin sensitivity.


*All individuals are unique. Your results can and will vary.

Bottom line: Sodium bicarbonate has a PH of 9 which may prevent absorption of Vitamin C.

ZO Skin Health Oil Control Pads

The acne treatment pads help normalize skin pores, remove oil, and smooth the skin surface. The pads contain high concentrations of alcohol and help them achieve these effects. However, alcohol-based products can stimulate the sebaceous gland to produce more oil, making the skin oilier and shinier.

Excess oil on the skin can cause more breakouts. Too much alcohol on the skin can also cause irritation, dryness, and disruption of the skin barrier. ZO Skin Health Oil Control pads also contain glycolic acid and salicylic acid, which are beneficial to the skin.

Bottom line: ZO Skin Health Oil Control Pads contain alcohol which may be harmful to the skin.

ZO Skin Health Daily Power Defense

The Daily Power Defense Serum is an antioxidant, although it does not contain many antioxidants only Vitamin E and retinol. Retinol in skincare products stimulates collagen production to help reduce signs of aging.

The serum contains another powerful ingredient, Matrixyl 3000, that acts as an anti-aging agent. Matrixyl 3000 is a trademarked peptide that combines two matrikines (palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7). The two work to restore the skin’s youthful appearance by signaling collagen production.


*All individuals are unique. Your results can and will vary.

Bottom line: ZO Skin Health Daily Power Defense serum contains peptides and retinols. However, the product contains fragrances with may cause sensitivity.

ZO Skin Health Growth Factor Serum

The growth serum has high concentrations of different silicones and humectants that help fight signs of aging. Humectants retain moisture and help plum up the skin, while silicones blur the appearance of wrinkles and fine lines. The effects of the serum are temporary and disappear once you wash it off.

The formula also contains Budlejja Davidii Meristem cells which have high concentrations of polyphenols. The plant stem cells help mitigate oxidative stress and inflammatory response.

Bottom line: the serum consists of silicones, humectants, plant stem cells, and growth factors.

ZO Skin Health Exfoliating Cleanser

The gel cleanser contains jojoba ester that gently exfoliates the skin to remove dead skin cells.

Similar to other cleansers, the product contains surfactants like Cocamidopropyl betaine and sodium Laureth sulfate. The surfactants attract and suspend dirt, oils, and other impurities on the skin and wash them away.

The exfoliating Cleanser also contains salicylic acid, which exfoliates the skin without clogging pores.

Bottom line: ZO Skin Health Exfoliating Cleanser contains surfactants, jojoba esters, and salicylic acid which helps exfoliate dead skin cells and unclog pores.

ZO Skin Health Vitamin C Self Activating

This vitamin C serum combines 10% pure vitamin C (ascorbic acid) with another stable vitamin C derivative (tetrahexyldecyl ascorbate)

Regardless of the derivative, all forms of vitamin C become ascorbic acid once absorbed into the skin. Ascorbic acid is an antioxidant that protects the skin from free radicals, fades dark spots, and brightens skin complexion.


*All individuals are unique. Your results can and will vary.

The formula also contains vitamin E which is a popular antioxidant, and together with vitamin C, they are referred to as network antioxidants.

Finally, the serum contains silicones and squalene that give the skin a silky texture, moisturize and soften the skin.

Bottom line: the vitamin C serum combines ingredients that help brighten, firm, and hydrate the skin.

ZO Skin Health Retinol Skin Brightener

Retinol Skin Brightener is a silky serum that brightens and evens the skin tone. The serum contains 1% retinol which gives great benefits to its users. Retinol reduces the appearance of wrinkles, improves skin firmness, evens skin tone, and unclog pores.

The product also includes vitamins C and E, soy isoflavones, glutathiones, and glucosamine that prevent the formation of age spots.

Bottom line: A moderate strength serum that even skin tone.

How Does Product Rate?

Feature Rating Comments
Safety 8 /10 The ingredients are lab tested, vegetarian friendly, cruelty free, prioritizes organic ingredients, created by certified dermatologist
Performance 7.5 / 10 Works well in the long term, the results may change with skin type
Average customer ratings 4.25/5 stars Each product has its own customer rating

What Are The Main Ingredients in ZO Skin Health Skin Care

Vitamin C

Vitamin C is a water-soluble vitamin that presents numerous skin benefits. It has antioxidant properties and helps remove oxidative species and unwanted substances from the body. Vitamin C also stimulates collagen production in the body.

A publication in the Nutrients journal reveals that vitamin C supports collagen stimulation and protects the skin against photo damage from UV rays.


Retinoids stimulate the production of collagen and new blood vessels in the skin. Collagen helps to fight the signs of aging.

The Advances in Dermatology and Allergology journal claims that vitamin A is a fat-soluble vitamin that helps fight age and improve the appearance of the skin.

Salicylic Acid

Salicylic acid helps prevent future acne by keeping pores clean and exfoliating the skin as explained in the content of Nourish max reviews.

A study in the Clinical, Cosmetic and Investigational Dermatology journal agrees that salicylic acid is used as a peeling agent to treat acne.

Glycolic acid

Glycolic acid is suitable for individuals with acne-prone and oily skin. Topical application of the acid on the skin helps remove dead skin cells, fight aging, clear acne, and brighten skin complexion.

According to the Clinical, Cosmetic and Investigational Dermatology journal, glycolic acid is used as a peel of and it helps with acne, melasma, hyperpigmentation, acne scars, and photo aging.

People Also Ask

Q: Where is ZO Skin Health Sold?

A: ZO Skin Health products are only available on their Physician’s online store and other approved Physicians.

Q: Does ZO Skin Health Have a Return Policy?

A: The brand offers a 30-day money-back guarantee on all their products. The refund is exclusive of shipping and handling fees.

Q: Is ZO Skin Health Vegan?

A: ZO Skin Health is not 100% vegan. However, it contains some products that are suitable for vegans.

Q: Is ZO Skin Health Cruelty Free?

A: Yes, the brand is cruelty-free

Q: What Are Some Alternatives to ZO Skin Health?

A: There are a couple of options for you to consider. One brand is No B.S. Skincare since they develop products that give long-term results. Another brand that combines the power of natural ingredients with science is Beverly Hills MD. Beverly Hills MD products are good for your skin and the environment as they do not contain harmful ingredients.

Q: How Does ZO Skin Health Compare with Obagi?

A: The major difference between these two brands is that Obagi Skincare products contain standard ingredients, like retinols, AHAs, vitamin C, and hydroquinone; while ZO Skin Health products contain innovative ingredients, such as ZCORE Complex and ZPRO.

Q: What Do the Customer’s Think of ZO Skin Health Products?

A: On the official website, ZO Skin Health reviews are generally positive. The brand only displays reviews with 5-star ratings making it too good to be true. Most of the customers are happy that the products delivered the results they were expecting.


ZO Skin Health develops products that helps restore skin elasticity, firmness, and texture. The natural ingredients stimulate the production of collagen, which repairs the skin barrier for softer, younger-looking skin. The brand uses safe ingredients free of toxic chemicals to manufacture this product.

Since each individual has a different skin type, results will vary. Consistent application of the skincare product allows you to see dramatic results. In case your skin reacts negatively, kindly discontinue use and find a suitable product for your skin.

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[1] Vitamin C in dermatology https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3673383/
[2] Retinoids: active molecules influencing skin structure formation in cosmetic and dermatological treatments https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791161/
[3] Salicylic acid as a peeling agent: a comprehensive review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554394/
[4] The Roles of Vitamin C in Skin Health https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579659/
[5] Glycolic acid peel therapy – a current review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875240/