What Are Wrinkle Fillers?

Wrinkle fillers are skincare products which aim to tighten and plump the complexion, smoothing fine lines, wrinkles, and creases. While some offer only temporary benefits, others work both short and long term to decrease signs of age and promote a more youthful appearance. According to Dermatologist Cory Bovenzi “wrinkle fillers are commonly used for hollow undereyes, hollow cheeks, prominent nasolabial folds, marionette lines, and lips. There are many formulations of fillers for these different areas to ensure you have natural facial movements and expressions.”

Our team of board-certified dermatologists evaluated the existing products on the market based on a range of criteria to determine the best wrinkle fillers available today. In this article, we’ll give you all the information you need to know about wrinkle fillers and provide you with details of the top selections.

Best Wrinkle Fillers

Our Top Wrinkle Fillers Picks

Best Deep Wrinkle Filler Beverly Hills MD Deep Wrinkle Filler
Best Soft-Focus Finish City Beauty Line-Blurring Wrinkle Filler
Best Serum for Deep Wrinkles ROC Retinol Correxion Deep Wrinkle Filler
Best Wrinkle Filler with Hyaluronic Acid SkinMedica HA5 Rejuvenating Hydrator
Best Quick-Absorbing Formula Filorga Time-Filler Wrinkle Correction Skin Cream
Best Hydrating L’Oreal Paris Collagen Moisture Filler
Best Anti-Aging Filler Fillhage
Best Lightweight Formula Dr. Brandt Needles No More Wrinkle Smoothing Cream
Best Hypoallergenic Formula Boots No. 7 Instant Illusion Wrinkle Filler
Best Wrinkle Filler For Pores Olay Regenerist Wrinkle and Pore Vanisher
Best For Sensitive Eyes Mary Kay Deep Wrinkle Filler
Best Instant Wrinkle Filler Cream For Oily Skin Estee Lauder Perfectionist Pro
Best For Laugh Lines Strivectin Wrinkle Filler
Best Wrinkle Filler For Eyes Instant FIRMx Temporary Face Tightener

It’s important to note that not every wrinkle filler will work for everyone, and your results may vary.

Which Wrinkle Filler Should I Use?

Are you ready to hear about some of the best wrinkle fillers on the market? We’ve researched numerous brands to seek out the most promising products in the industry. Here we present the top wrinkle fillers available today.

Beverly Hills MD Deep Wrinkle Filler

Beverly Hills MD Deep Wrinkle Filler is a high-end anti-aging skin care product. Its exclusive bio-lifting technology reduces the appearance of fine lines, creases, and deep wrinkles rapidly. The product contains a blend of powerful, natural ingredients that are intended to hydrate, firm, and plump the skin to reduce the appearance of wrinkles.

Review

The fine lines around my mouth have definitely improved! I’m hoping that with continued use, the deeper wrinkles will improve even more. I am very pleased with this facial wrinkle filler and would strongly recommend it!~ Christiane Beard

Key Facts

Container Type: Tube | Features: Anti-inflammatory | Skin Type: For All Skin Types | Size: 2 fl oz (60 ml) | Form: Cream | Brand: Beverly Hills MD


City Beauty Line-Blurring Wrinkle Filler

City Beauty Line-Blurring Wrinkle Filler is a wrinkle filler that is designed to reduce the appearance of fine lines and wrinkles. It contains a blend of peptides, hyaluronic acid, and other ingredients that work together to smooth and plump the skin. It is suitable for all skin types and can be used as needed.

Review

I love this product! I’m 60 years old and it has significantly reduced my wrinkles on my forehead and also on my upper lip area. If you haven’t tried this product before it’s a must! Thank you City Beauty for your great care towards creating beauty products like these. This product makes me feel forever young!~ Mary Ann Young

Key Facts

Container Type: Pump Bottle | Skin Type: For All Skin Types | Size: 0.25 fl oz (7.5 ml) | Form: Cream | Brand: City Beauty


RoC Retinol Correxion Deep Wrinkle Filler

This dual-action intensive wrinkle filler is formulated with retinol & hydrating hyaluronic acid. According to the manufacturer, this roc wrinkles filler can diminish the deep wrinkles within 4 weeks of daily use which helps improve the overall texture and tone of the skin, which makes it one of the best wrinkle filler for deep wrinkles. Look for the ROC deep wrinkle filler reviews to know more about it.

Review

This wrinkle filler for face is beneficial for fine wrinkles. It removes deep wrinkles and works well with their moisturizer to give my skin a clear appearance. Dark and dry spots have been reduced.~ Paul H.

Key Facts

Container Type: Tube | Features: Anti-Aging, Deep Wrinkles | Skin Type: For All Skin Types | Size: 1 fl oz (30 ml) | Form: Cream | Brand: RoC


SkinMedica HA5 Rejuvenating Hydrator

It is a hydrating serum that contains five different forms of hyaluronic acid to provide instant and long-term hydration to the skin. It is designed to smooth the appearance of fine lines and wrinkles and improve the texture and roughness of the skin. It is suitable for all skin types and can be used twice daily.

Review

This Skinmedica serum is pricey but it is totally worth every single penny! The bottle usually lasts about 6-7 months for me, which makes this even more worth the price! You WILL see improvement in your skin from day one of using, I use it under a BB cream that I use as foundation, and it is an excellent base layer for foundation, whether using a cream or mineral foundation!~ Jodi Bowman

Key Facts

Container Type: Pump Bottle | Features: HA5 Rejuvenating Hydrator | Skin Type: For All Skin Types | Size: 2 fl oz (60 ml) | Form: Serum | Brand: SkinMedica


Filorga Time-Filler Wrinkle Correction Skin Cream

Filorga Time-Filler is an all-in-one anti-aging face cream formulated with a powerful hyaluronic acid and peptide treatment that works to plump deep wrinkles and hydrate skin to minimize surface wrinkles for 50% fewer wrinkles in 2 months.

Review

I’ve been using time filler for a few months now and have received many compliments on my skin. I really love that I can put it on at any time and it never feels heavy or sticky.~ Denise

Key Facts

Container Type: Jar | Features: Improves Wrinkles & Skin Texture | Skin Type: Normal | Size: 1.69 fl oz (50 ml) | Form: Cream | Brand: Laboratories Filorga Paris


L’Oreal Paris Collagen Moisture Filler

L’Oréal Paris Collagen Moisture Filler Cream delivers intense hydration to the skin on a daily basis, helping to fill in the appearance of fine lines and wrinkles, resulting in smoother, plumper skin that is more nourished and appears younger.

Review

Just smooth, creamy hydration that replenishes skin without leaving a greasy residue. One of the best collagen filler!~ Gabberzak

Key Facts

Container Type: Jar | Features: Treating Wrinkles, Moisturize | Skin Type: Normal | Size: 1.7 fl oz (50 ml) | Form: Cream | Brand: L’Oreal Paris


Fillhage

FillHAge is a facial rejuvenation product used to fill in wrinkles, sagging skin, and fine lines. It is a needle-free anti-aging filler collection of six products. These products are intended to hydrate and plump the skin while also reducing wrinkles and lines and providing a long-lasting, natural-looking result.

Review

This is my preferred wrinkle filler. It has tightened my skin and given it a beautiful shine. After 4 weeks, the skin is much smoother and wrinkle-free. ~ Amanda S.

Key Facts

Container Type: 6 Bottles | Features: Remove Wrinkles, Fine Lines, Upper-Lip Lines & Sagging | Skin Type: Normal | Size: One in 5ml | Form: Cream | Brand: FillHage


Dr. Brandt Needles No More Wrinkle Smoothing Cream

Needles No More Wrinkle Smoothing Cream is a light cream that firms and protects the skin while smoothing the appearance of expression lines and wrinkles. The cream contains a blend of ingredients that work together to help hydrate and firm the skin, as well as to minimize the look of wrinkles.

Review

Dr. Brandt products are fantastic. I purchased the no more needles eye cream for my mother and received this as a sample. She stated that after just one use, her skin felt firmer. ~ Christina R.

Key Facts

Container Type: Bottle | Features: Light Scent | Skin Type:For All Skin Types | Size: 0.5 fl oz (15ml) | Form: Cream | Brand: Dr. Brandt Skincare


Boots No. 7 Instant Illusion Wrinkle Filler

No7’s Instant Illusion Wrinkle Filler instantly rejuvenates skin with it’s clear, silicone-based gel that is applied to the skin and works by filling in wrinkles and smoothing out the surface of the skin. The light velvety-soft formula creates an instant illusion of smoother, more radiant, and younger-looking skin.

Review

Because I don’t wear foundation, I need a wrinkle filler that doesn’t look plastic but does the job. That is exactly what this one does. It is a fantastic wrinkle filler. ~ Eddie

Key Facts

Container Type: Tube | Features: Smoother, Radiant and Youthful | Skin Type:For All Skin Types | Size: 1 fl oz (30ml) | Form: Cream | Brand: No.7


Olay Regenerist Instant Fix Wrinkle & Pore Vanisher

This revolutionary formula fills lines and creases to reduce the appearance of crow’s feet and wrinkles. A precision-tipped applicator delivers treatment precisely to key wrinkle-prone areas such as the eyes, mouth, and forehead. The dual-action process fills wrinkles and seals the surface with a micro-bonding network. In addition, its light-diffusing particles soften the appearance of pores, giving your skin a more even finish.

Review

I absolutely adore Olay Regenerist Instant Wrinkle Fixer and now I know how much to use. It is effective for me. Thank you very much, Olay. ~ Marjorie

Key Facts

Container Type: Tube | Features: Fine Lines & Wrinkles Aging | Skin Type:For All Skin Types | Size: 1 fl oz (30ml) | Form: Cream | Brand: Olay


Mary Kay TimeWise Repair Volu-Fill Deep Wrinkle Filler

Volu-Fill™ Deep Wrinkle Filler is designed to fill in and visibly plump areas like where facial expressions have left their mark on your forehead, around your lips and eyes, and even those difficult-to-treat frown lines between your brows or smile lines that can frame your mouth from nose to chin. It is one of the best wrinkle fillers that affect the appearance of all six wrinkle zones, and this advanced formula does exactly that.

Review

I’ve been using Time Wise Volu Fil for about 6 months and have seen a significant improvement in the lines around my mouth. ~ Allie

Key Facts

Container Type: Tube | Features: Minimizes Deep Wrinkles, Maintains Skin Moisture | Skin Type:For All Skin Types | Size: 2 fl oz (60ml) | Form: Cream | Brand: Mary Kay


Estee Lauder Perfectionist Pro Instant Wrinkle Filler

This Best Instant Wrinkle Filler helps fill facial lines and wrinkles, promoting smoother, younger-looking skin. Its anti-aging formula includes a concentrated tri-polymer blend of advanced filling spheres and blurring optics, as well as skin-plumping sodium hyaluronate. Furthermore, this formula provides a smooth foundation for makeup as well as a firmer, more youthful appearance. Therefore, it is the best wrinkle filler cream on the market.

Review

The most effective wrinkle filler! I’ve been using it for a long time. Expensive, but well worth it! Furthermore, it appears to work best over foundation. ~ Anne K.

Key Facts

Container Type: Tube | Features: Fills Facial Lines and Wrinkles | Skin Type:Oily, Combination, Dry, Normal | Size: 0.5 fl oz (15ml) | Form: Cream | Brand: Estee Lauder


StriVectin Anti-Wrinkle High-Potency Wrinkle Filler

StriVectin High-Potency Wrinkle Filler is a concentrated treatment that addresses wrinkles in three ways. It contains a blend of peptides that help stimulate collagen production, which can help improve the elasticity and firmness of the skin over time. This product also softens and hydrates skin over time, making future lines and wrinkles less visible.

Review

I’m 58 years old and use this product under my face cream in the morning and at night. I like how it warms my skin and makes it feel soft.~ Kimberly L.

Key Facts

Container Type: Pump Bottle | Skin Type: For All Skin Types | Size: 0.5 fl oz (15ml) | Form: Serum | Brand: StriVectin


Instant FIRMx Temporary Face Tightener

It is a is a fast-acting firming treatment that is designed to instantly tighten and firm the skin. It contains a blend of firming agents, including marine collagen, caffeine, and hyaluronic acid, that work together to provide a temporary tightening effect. It is suitable for all skin types and can be used as needed.

Review

Could not believe it actually worked! I have deep wrinkles, not fine lines. They were minimized and the puffiness that is the BAGS under my eyes disappeared. I did end up putting more on after my foundation. Still learning how to apply it correctly.~ Kim49

Key Facts

Container Type: Tube | Skin Type: For All Skin Types | Size: 3.4 fl oz (100 ml) | Form: Serum | Brand: Peter Thomas Roth


How Do They Work?

Wrinkle fillers include ingredients which increase levels of collagen and elastin that may have declined with time. This makes the skin tighter, more elastic, and it helps to smooth and reduce the depth of wrinkles, creases, and fine lines.

Cosmetic Dermatologist Dr. Dmitriy Schwarzburg explains, “As we age, our skin produces increasingly less collagen, causing fine lines to develop into wrinkles.

In addition, facial volume and fat loss with age result in dark under-eye circles, and mid-face hollowness, which is often observed in people in their early to mid-twenties and beyond [1].”

An article in Plastics and Aesthetic Research by David M. Reilly and Jennifer Lozano discussed the importance of collagen for skin health throughout life [2].

These products all include deeply hydrating substances like glycerin and hyaluronic acid which boost moisture levels to give the skin added volume. This further reduces the appearance of signs of age, as well as eliminating dryness.

A literature review by Bruna Bravo, et al published in Dermatologic Therapy discussed the evidence supporting the benefits of hyaluronic acid in improving skin quality and decreasing signs of aging [3].

Some fillers contain polymers which temporarily fill creases and crevices in the skin, for a smooth, wrinkle, free, youthful appearance quickly.

Wrinkle filler also includes anti-inflammatory agents which can decrease redness and swelling, and antioxidants which eliminate harmful free radicals. This results in lower levels of oxidative stress, repairing damage and helping to decrease signs of age.

A review published in the Journal of Dermatological Science examined the research showing the key role of antioxidants in skin anti-aging [4].

What Are The Key Ingredients In Wrinkle Fillers?

These are some of the deep wrinkle filler ingredients that you should look for when selecting your anti-aging product.

Hyaluronic Acid

This is a substance that exists naturally in the skin, eyes, and connective tissue, and it draws massive amount of hydration for deep moisturizing benefits. This plumps the skin, smoothing wrinkles, lines, and creases, while also eliminating dryness. According to Dr. Jerry Friedman, North Jersey Oral & Maxillofacial Surgery “Fillers contain hyaluronic acid, or HA, which is a naturally occurring substance in the body that keeps the tissues moisturized. This treatment also helps in the reduction of lines and wrinkles.”

A study by S. Manjula Jegasothy, MD, et al published in The Journal of Clinical and Aesthetic Dermatology showed that after 2 and 8 weeks of treatment a nano hyaluronic acid formula significantly improved skin firmness, elasticity, hydration, and reduced wrinkles [5].

Collagen or Peptides

Peptides are strings of amino acids which produce the protein collagen. As we explained in our Drmtlgy Advanced Eye Cream review, levels of collagen decrease with age. The boost in amount tightens the skin, improves elasticity, and smooths wrinkles and fine lines on the complexion.

A 4 week study published in the International Journal of Molecular Science by Young In Lee and Sang Gyu Lee, et al showed that regular application of a topical collagen tripeptide offered anti-aging benefits [6].

Alpha Hydroxy Acids

These are acids which occur naturally, usually in fruits. They have exfoliating benefits for the skin, removing dead skin cells, dirt, and oil for a fresher, healthier complexion.

In addition, these acids boost levels of collagen, for skin that is firmer and smoother of wrinkles and fine lines. An article in Jundishapur Journal of Natural Pharmaceutical Products by Eskandar Moghimipour discussed alpha hydroxy acids and their benefits as anti-aging agents [7].

“AHAs like glycolic acid are excellent for improving the appearance of fine lines and wrinkles. As exfoliants, they promote skin cell turnover which sloughs off dead skin to reveal fresher, smoother skin underneath. This can help reduce the look of wrinkles over time with consistent use.” ~ Rachel Nazarian, MD

Skin Polymers

As we described in our review of Deep Wrinkle Filler, these are natural substances with large molecules which serve to temporarily fill in areas on the skin and decrease the appearance of wrinkles, fine lines, and crevices almost immediately.

A randomized controlled trial published in the Journal of Cosmetic Science by Marc N G de Mul and Tanya Uddin, et al concluded that polymers offered immediate anti-aging benefits, increasing skin firmness and reducing wrinkle size [8].

Pros and Cons of Deep Wrinkle Fillers

Pros

  1. These products can smooth fine lines, creases, and wrinkles.
  2. The best wrinkle fillers can visibly plump the complexion.
  3. They provide deep hydration and can eliminate dryness.
  4. Natural wrinkle fillers can enhance skin texture.
  5. These formulas can improve skin elasticity.

Cons

  1. While some products offer long-term results, others are only temporary fillers.
  2. The results will vary based on the product and individual.
  3. Some of the popular brands may run low stock from time to time.

Different Types Of Wrinkle Fillers

Wrinkle fillers, also known as dermal fillers, are substances injected into the skin to smooth wrinkles and make them less noticeable. There are several types of wrinkle fillers, each with its own unique characteristics and benefits. The most common types of wrinkle fillers include:

Hyaluronic Acid Fillers: These are the most popular category of wrinkle fillers. Hyaluronic acid is a natural substance found in the body that keeps the skin hydrated. They are used to improve the skin’s contour and reduce depressions in the skin due to scars, injury, or lines. The results typically last 6 to 12 months.

Calcium Hydroxylapatite Fillers: Calcium hydroxylapatite fillers are a type of cosmetic injection that can help improve the appearance of facial wrinkles and sagging skin. They are made of a synthetic material that stimulates the natural production of collagen, a protein that gives the skin its firmness and elasticity.

This fillers are injected under the skin in areas where there is volume loss or deep creases, such as the cheeks, temples, chin, or nasolabial folds. The injection process is usually done in multiple sessions, spaced a few weeks apart, to achieve the desired results. The effects of calcium hydroxylapatite fillers can last up to two years or more.

Autologous Fat Injections: Autologous fat injections are a type of cosmetic injection that can help improve the appearance of facial wrinkles and sagging skin. They use your own body fat, taken from another area such as the hips, thighs, abdomen, or neck, to add or restore volume to specific areas of the face.

The procedure involves extracting excess fat from one area of the body using a gentle liposuction technique, processing the fat cells with a centrifuge or filter, and then injecting the purified harvested fat into the treatment area, to plump, lift, smooth, and reduce volume loss. The injection process is usually done in multiple sessions, spaced a few weeks apart, to achieve the desired results.

Poly-L-lactic Acid (Sculptra): Poly-lactic acid (Sculptra) filler is a type of cosmetic injection that can help improve the appearance of facial wrinkles and sagging skin. It is made of a synthetic material that stimulates the natural production of collagen, a protein that gives the skin its firmness and elasticity.

Sculptra filler is injected under the skin in areas where there is volume loss or deep creases, such as the cheeks, temples, chin, or nasolabial folds. The injection process is usually done in multiple sessions, spaced a few weeks apart, to achieve the desired results.

Polyalkylimide: Polyalkylimide filler is a type of cosmetic injection that can help improve the appearance of facial wrinkles and sagging skin. It is made of a synthetic material that stimulates the natural production of collagen, a protein that gives the skin its firmness and elasticity.

Polyalkylide filler is injected under the skin in areas where there is volume loss or deep creases, such as the cheeks, temples, chin, or nasolabial folds. The injection process is usually done in multiple sessions, spaced a few weeks apart, to achieve the desired results.

Permanent Soft Tissue Fillers (Bellafill): Bellafill is a type of permanent soft tissue filler that can help improve the appearance of facial wrinkles and sagging skin, especially around the mouth. It is made of a synthetic material that stimulates the natural production of collagen, a protein that gives the skin its firmness and elasticity. Bellafill is injected under the skin in areas where there is volume loss or deep creases, and it can last up to five years or more.

How Did We Evaluate The Best Instant Deep Wrinkle Fillers?

Our team of board certified dermatologists examined the range of products on the market to determine the best wrinkle fillers on the market using some of the following criteria. You should look for the same features when doing your own research.

Ingredients – The best products include all-natural ingredients with no artificial or chemical additives. A quality wrinkle filler should ideally include collagen-boosting substances, alpha hydroxy acids, polymers, and hydrating ingredients like glycerin and hyaluronic acid.

Safety – Products are safest if the production takes place in an FDA registered facility and follows strict safety standards in manufacturing and testing, ideally GMP (Good Manufacturing Practices).

Manufacturer – Although there are little-known manufacturers which produce quality products, it’s generally best to purchase from a well-known company which has a reputation for making quality, safe skincare.

Value for Price – Compare different brands in terms of what they have to offer for the cost. Don’t automatically assume that an expensive brand equals a high quality filler, as it’s not always the case.

Refund Policy or Guarantee – Before buying a product, check that the manufacturer offers at least a 30-60 day guarantee or return policy to give you a chance to see if the formula works for you. Any reputable manufacturer that believes in their product will offer a decent guarantee.

How Do You Use Wrinkle Fillers?

The specific directions for application will depend on the product, so follow them as stated. For most fillers, you use them following cleansing and toning in the morning to the areas where you want to reduce wrinkles. Pat gently during application and follow up with your sunscreen and then makeup if you wish.

FAQs

Q: What is the Most Natural Wrinkle Filler?

A: When it comes to wrinkle filler ingredients, hyaluronic acid is the most natural substance. It exists in the skin and levels decline with age. Using a filler with this ingredient works to hydrate and plump the complexion, smoothing wrinkles and lines.

Q: What Are the Best Organic Wrinkle Fillers?

A: The best natural wrinkle fillers are the brands included in this article, as evaluated by our team of dermatological experts based on a number of rigid criteria.

If you want to research other brands, look for products from reputable companies that are 100% natural and free of additives. Wrinkle fillers that work include ingredients like polymers, collagen, peptides, and hyaluronic acid, and are high value for the cost.

Q: Where Can I Purchase a Wrinkle Filler?

A: There are a number of high quality wrinkle fillers available from online retailers as well as from pharmacies, department stores, and cosmetics shops. However, availability of specific products will vary based on the brand.

Q: Are Wrinkle Fillers Safe?

A: The best wrinkle fillers, including the ones we have recommended in this article, use all-natural ingredients and are safe for most users. Naturally if you have allergies you should check the list to make sure the product is suitable for you.

However, if you are researching brands, you have to look at the ingredients and the manufacturing practices to ensure complete safety.

Ideally, the manufacturing should take place in an FDA registered, GMP compliant facility. Look for a brand with 100% organic ingredients, free of chemical or synthetic additives.

Q: Who Should Use a Wrinkle Filler?

A: Wrinkle fillers that work are ideal for anyone looking for a natural product to reduce the appearance of wrinkles, lines, and creases on their complexion due to aging, and improve skin texture. They may help prevent future wrinkles but are primarily intended for people who already have existing signs of age.

Q: How Can I Fill My Wrinkles At Home?

A: While professional treatments like fillers are often the most effective for reducing wrinkles, there are several at-home methods and products you can use to help minimize the appearance of wrinkles. You can use products with Retinol, Peptides, Glycolic acid, and many more ingredients that are effective on your wrinkles.

Q: How Long Does It Take for Wrinkle Fillers To Work?

A: In general, temporary fillers work immediately or may take 2 weeks while semi-permanent and permanent options take 3-6 months for their full collagen-stimulating effects.

Q: Are Wrinkle Fillers Appropriate for All Skin Types?

A: It’s best to consult a board-certified dermatologist or plastic surgeon to determine if fillers are suitable given an individual’s unique skin type, concerns, and goals. A patch test is a good option in some cases to determine the sensitivity.

Quick Comparison Table

Product Rating Key Ingredients Return Policy
Beverly Hills MD Deep Wrinkle FillerBeverly Hills MD Deep Wrinkle FillerPrice. $125 Rating Tightenyl, Diamond Powder, Polymer Blend 60-Day Money Back Guarantee
L’Oreal Paris Collagen Moisture FillerL’Oreal Paris Collagen Moisture FillerPrice. $11.49 Rating Shea Butter, Soluble Collagen, Boswellia Serrata, Glycerin 45-Day Satisfaction Guarantee
Boots #7 Instant Illusion Wrinkle FillerBoots #7 Instant Illusion Wrinkle FillerPrice. $19.99 Rating Cyclopentasiloxane, Glycerin, Silica, Butylene Glycol 14-Day Return Policy
Estee Lauder Perfectionist Pro Instant Wrinkle FillerEstee Lauder Perfectionist Pro Instant Wrinkle FillerPrice. $126 Rating Acetyl Hexapeptide 8, Laminaria Digitata Extract, Siegesbeckia Orientalis Extract 60-Day Return Policy

Conclusion

Natural wrinkle fillers can have a significant impact on reducing signs of age on the skin, for both short and long term benefits. These products boost collagen and elastin levels for tighter, more elastic skin smooth of creases, wrinkles, and fine lines. They also deeply hydrate and plump the skin for further wrinkle reduction.

In this article, we have provided recommendations for the best wrinkle fillers according to leading, board-certified dermatologists. All of the products on our list are safe, effective, include science-backed, natural ingredients, and are from leading skin care manufacturers.

In addition, they have primarily positive feedback from reviewers reporting superior wrinkle fillers before and after results. This comprehensive guide should help you find the ideal brand to suit your needs.

Joanna McGetrick, MD, FAAD

By Joanna McGetrick, MD, FAAD

Dr. Joanna McGetrick, MD is a Dermatologist in Orlando, Florida. She is board certified by the American Board of Dermatology. She focuses on a combination of complex medical dermatology, surgical procedures, and cosmetic dermatology.

13 sources

[1] Skin Collagen Through The Lifestages: Importance For Skin Health And Beauty: https://parjournal.net/article/view/3863
[2] Benefits Of Topical Hyaluronic Acid For Skin Quality And Signs Of Skin Aging: From Literature Review To Clinical Evidence:https://onlinelibrary.wiley.com/doi/10.1111/dth.15903
[3] Role Of Antioxidants In The Skin: Anti-Aging Effects:https://pubmed.ncbi.nlm.nih.gov/20399614/
[4] Efficacy Of A New Topical Nano-Hyaluronic Acid In Humans:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970829/
[5] Effect of a Topical Collagen Tripeptide on Antiaging and Inhibition of Glycation of the Skin: A Pilot Study:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835374/
[6] Hydroxy Acids, the Most Widely Used Anti-aging Agents:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941867/
[7] Reducing Facial Wrinkle Size and Increasing Skin Firmness Using Skin Care Polymers:https://pubmed.ncbi.nlm.nih.gov/29799810/
[8] Effect of a Topical Collagen Tripeptide on Antiaging and Inhibition of Glycation of the Skin: A Pilot Study:https://www.mdpi.com/1422-0067/23/3/1101
[9] Hyaluronic Acid: A Key Molecule In Skin Aging:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886/
[10] Role Of Topical Peptides In Preventing Or Treating Aged Skin:https://pubmed.ncbi.nlm.nih.gov/19570099/
[11] https://www.researchgate.net/publication/259404750_Silicone_Polymers_in_Skin_Care
[12] Micro And Nanocrystalline Diamond Skin Care Products And Their Applications: https://oaji.net/articles/2017/731-1545730711.pdf