What is Needle-less Serum?

Drmtlgy Needle-less Serum is a high-level anti-aging formula composed of 100% pure, organically-sourced ingredients. It can tighten the skin, improve elasticity, and smooth wrinkles and lines, especially around the mouth, eyes, and forehead.

It also deeply hydrates, repairs skin damage, and protects from UV rays and pollution. A team of dermatologists developed Drmtlgy NeedleLess Serum, and many others worldwide recommend it. Having researched numerous anti-aging serums, in my opinion this is one of the top brands on the market.

Brand Highlights

  • Drmtlgy Needle Less Serum includes 100% pure, organic ingredients.
  • The formula is suitable for all skin types, including sensitive.
  • The manufacturer is completely cruelty-free.
  • They manufacturer in the USA following GMP safety standards.

Fast Facts

Needle-less Serum

Best For: All skin types.
Uses: Smooth wrinkles and lines, Anti-aging, Acne, and Dryness
Active Ingredients: Niacinamide, Glucosamine, Ceramides, Peptides, Bambusa Vulgaris Leaf/Stem Extract, Hyaluronic Acid, Pea Extract, Sodium Chondroitin Sulfate, Glycosaminoglycans
Price: $69
About The Brand: The manufacturer of Needle-less Serum is a reputable company called Drmtlgy, LLC, founded in 2017 in Los Angeles, California. They are a top skincare brand which uses medical grade, all-natural ingredients in their formulations. Their products target issues like anti-aging, acne, dryness and numerous other concerns.
Buy Now: Official Website

Pros and Cons of Needle Less Serum


  1. Drmtlgy Needle-less Serum deeply moisturizes and eliminates dryness.
  2. This formula can smooth wrinkles and fine lines around the mouth, forehead, and eyes.
  3. Needle-less Serum repairs damage to the skin barrier.
  4. This serum can give your skin a good glowing appearance.
  5. Needle-less Serum can protect from harmful UV rays.


  1. The serum is only available online at the moment.
  2. The results will vary depending on the person.
  3. Drmtlgy Needle-less Serum formula could include other organic ingredients.

How Does Drmtlgy Needle-less Serum Work?

Drmtlgy Needle-Less Serum is high in peptides, which are chains of amino acids which stimulate collagen and elastin production. This tightens the skin, improves elasticity, and smooths wrinkles and lines.

A study in the Journal of Photochemistry and Photobiology B: Biology concluded that collagen and elastin peptides has potent anti-aging benefits. [1]

The formula is incredibly hydrating, deeply moisturizing the skin and eliminating dryness. It contains ingredients which form a barrier, keeping the moisture inside and preventing harmful bacteria from entering. The liquid also plumps the skin, for further smoothing of lines and wrinkles.

An article in the Journal of the European Academy of Dermatology and Venereology discussed the clinical benefits of moisturizers. [2]

There are ingredients in Drmtlgy Needle-less Serum which improve blood flow, and this generally boosts the health of the skin as well as transmitting a radiance. Anti-inflammatory agents decrease swelling and redness and may help to treat certain skin conditions.

Drmtlgy Needle-Less Serum is very rich in antioxidants, which work to destroy free radicals on the complexion and lower oxidative stress. This enhances the skin’s immunity, repairs damage, and protects from harmful environmental agents like UV rays.

Check the Official Websiteto Purchase this Product.

What are the Needle Less Serum Ingredients?

These are some of the primary active Needle-less Serum ingredients:


Ceramides are essential components of the skin’s barrier function, helping to prevent moisture loss and protect against environmental damage. Topical and oral supplementation with ceramides can improve skin hydration, texture, and overall health says Dr. Joshua Zeichner

Levels of ceramides deplete with age, which can cause dry, flaky skin. The added amounts greatly boost hydration, plump the skin, and help smooth wrinkles and lines.

An article in the Journal of Dermatological Science discussed ceramides and their function in skin homeostasis and inflammatory skin diseases. [3]

Our Drmtlgy Peptide Night Cream Review article highlights the key ingredients that make this product so effective, including ceramides which help support the skin barrier and improve moisture retention.

Sodium Chondroitin Sulfate

This is a deeply hydrating substance which exists naturally in the connective tissue, helping to repair and lubricate the joints and cartilage. It can also deeply hydrate the skin and help fade wrinkles. It has anti-inflammatory agents which can condition, soothe, and heal.

There is some evidence to suggest that topical application of sodium chondroitin sulfate may have anti-inflammatory and wound-healing properties, which could potentially benefit the skin says Dr. Michelle Green

A study in the Asian Journal of Pharmaceutical Science concluded that sodium chondroitin sulfate deeply hydrated the skin after only one application. [4]


This is Vitamin B3, one of the most potent skincare ingredient. It hydrates, restores, and builds keratin which strengthens the skin barrier as referenced in the City Beauty Invisicrepe Body Balm Reviews article. Niacinamide has anti-inflammatory benefits which decrease redness and swelling and can even treat some skin conditions like eczema.

Niacinamide is a versatile ingredient with many benefits for the skin. It can help improve skin texture and tone, reduce inflammation, regulate oil production, and even help prevent the formation of fine lines and wrinkles says Dr. Patricia Wexler

It can boost cellular immunity, repair damage, and protect from harmful agents like UV rays. A study in the Journal of the American Academy of Dermatology found that niacinamide could decrease wrinkles, yellowness, hyperpigmentation, and redness. [5]


Peptides are short chains of amino acids that can signal cells in the skin to produce more collagen, which is essential for maintaining skin elasticity and preventing wrinkles says Dr. Rachel Nazarian. Peptides can also decrease redness and inflammation on the complexion.

They have antioxidant potential, and can boost the skin’s immunity, repair, and protect from damage. A review in Cosmetics explored the anti-aging benefits of topical peptide treatments. [6]

Drmtlgy Needle-less Serum (FAQs)

Q: Where to Buy Needle-less Serum?

A: Although Drmtlgy brand is actually available from a number of retailers, at the moment I can only find this particular item for sale on the manufacturer’s official website. You can buy it once for the Needle-less Serum price of $69 or subscribe to save 20% and pay $55.

At the moment, they are offering a promo – click on the link at the top of the page, and they will send another 20% off to your e-mail address.

Q: Is Needle-less Serum Worth It?

A: While the price is not cheap, it’s not overly expensive for the quality of the product. I found that it was very clear from the Needle-less Serum reviews that most users loved this product and the Needle-less Serum before and after, and felt it was worth every penny.

Q: What is the Needle-less Serum Return Policy?

A: Drmtlgy has a 60-day return policy. If you are not happy with the serum, get in touch with the company by phone or email for instructions. Then send it back within 60 days of the original date of purchase. You should get a full refund, excluding the shipping costs.

Q: Is Needle-less Serum Cruelty-Free?

A: Yes, Drmtlgy is a completely, 100% cruelty-free company which will never test their products on animals or work with associates or suppliers who do so.

Q: What Sets Needle-less Serum Apart From the Competition?

A: The quality of the Needle-less Serum formula and the potency is superior to many other anti-aging serums on the market. The use their own proprietary Cerapep® Technology which has a rich mix of powerful peptides and ceramides.

Drmtlgy Needle-Less Serum Reviews – What Do Real Users Say?

After reading through many of the Needle-less Serum reviews, I concluded that this was one of the best anti-aging serums around. Customers said it worked really fast to smooth wrinkles and lines, get rid of dry skin, and give their complexion a rosy, healthy look.

Here are some of the top comments, which I picked out so that you could get an idea of what people are saying about Needle-less Serum.

Great product

I am 66 years old and will never go under the knife. I started with the small size bottle to give it a try. Recently reordered the large bottle. This serum gives subtle, but noticeable, results. I will definitely continue using.
Jane E..

Needle-less Serum

I love this product! This has helped to provide a higher level of moisturizing to my skin that is weightless and never sticky like some other hyaluronic acids. This layers well under other Drmtlgy products and my makeup. Highly recommend.
Renaye Razewski.

Needleless Serum

This serum is amazing! Been using it for short of a week and loved it so much I came back online and ordered several more products!
Debra R.

Worth it!!

After about a week of consistent use I noticed a visible difference! I have better skin texture and pore size.

Official Video Of Needle Less Serum | Drmtlgy

How Do the Needle-less Serum Features Rate?

Feature Stars
Manufacturer 5/5
Safety 5/5
Ingredients 4.5/5
Price 4.8/5

Needle-less Serum Review – Conclusion

Needle-less Serum is a dermatologist-developed anti aging serum which promises to tighten the skin, improve elasticity, smooth wrinkles and lines, repair, protect, decrease inflammation, hydrate, and get rid of dry, flaky skin. Made by a highly reputable manufacturer, this is a deeply enriching skincare product.

I have read most of the Needle-less Serum reviews, and I found that the majority of them were very positive. Customers loved the anti-aging benefits, and said it worked fast to give them a younger appearance and boost their confidence.

Drmtlgy Needless Serum is a high-quality organic formula which is highly recommended by dermat.

Where to Buy?

Check the Official Website to Purchase this Product.

5 sources

[1] The Effects And Mechanism Of Collagen Peptide And Elastin Peptide On Skin Aging Induced By D-Galactose Combined With Ultraviolet Radiation: https://www.sciencedirect.com/science/article/abs/pii/S1011134420304140
[2] The Clinical Benefits of Moisturizers
[3] The Role Of Ceramides In Skin Homeostasis And Inflammatory Skin Diseases: https://www.sciencedirect.com/science/article/abs/pii/S0923181119303706
[4] https://www.researchgate.net/publication/267973121_Combined_effect_of_sodium_chondroitin_sodium_hyaluronate_on_skin_moisturization_following_single_and_repeated_application
[5] Topical Niacinamide-Containing Product Reduces Facial Skin Sallowness (Yellowing): https://www.jaad.org/article/S0190-9622(04)02915-9/fulltext