Skin Care Product Reviews

Dr. Perricone MD Review – Do Perricone MD Skin Care Products Really Work?

Perricone MD is the global leader in anti-aging skincare. Find the best Perricone products, ingredients, consumer reviews & more.
By Dermspotlight Staff,
Updated May 7, 2021

Dermspotlight Fact-Checking Standards

The content on Dermspotlight website is medically reviewed or fact checked to ensure factually accurate information.

With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. Note that the numbers in parentheses (1, 2, etc.) are clickable links to these studies. does not assume liability for any actions undertaken after visiting these pages, and does not assume liability if one misuses products. and its Editors do not ensure that unforeseen side effects will not occur even at the proper dosages, and thereby does not assume liability for any side effects from products, creams, or practices hosted under the domain of

Dermspotlight is primarily funded through affiliate commissions. Meaning, when you purchase a product via a link from our website, we earn a small commission on the sale from the retailer (at no additional cost to you). Dermspotlight is a member of numerous affiliate networks representing hundreds of cleans beauty brands and retailers. Because of this, no single brand or company has control over our review decisions.

MEDICAL DISCLAIMER: The content on this website is strictly the opinion of the writers of Dermspotlight and is for informational and educational purposes only. It is not intended to act as medical advice or to substitute medical advice or adequate treatment from a qualified medical professional. All viewers of this content are advised to consult a qualified medical professional (such as a dermatologist) regarding specific skin care and health questions. Dermspotlight does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content.

We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. All of our content is reviewed by dermatologists, plastic surgeons, and leading physicians in the beauty and aesthetics space.

Our goal is to not have a single piece of inaccurate information on this website. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us.

About Dr. Perricone MD Products

Dr. Perricone MD products are cosmeceuticals that claim to use a holistic approach. Its line of products has expanded over the years to include “no makeup” makeup products and dietary supplements.

Apart from these products, the brand also features a special 3 days and 28 days diet plan to complement the working of the products. This diet plan involves eating antioxidant-rich foods, vitamin supplements, and high-quality proteins.

Who is Dr. Perricone?

Dr. Perricone is a celebrity dermatologist who is known to be the first to embrace a holistic, healthcare, and wellness approach through his products. He does not believe in injections to counter aging signs as he theorizes that aging is an inflammatory disease at the cellular level therefore, it can be prevented.

Dr. Perricone is also an author of dermatology books such as “The Wrinkle Cure”, “Ageless Face, Ageless Mind”, and “Forever Young” among others.

What Does Perricone MD sell?

This brand sells a wide range of skincare products, makeups, and supplements. Some of the products include;

  • Perricone MD cold plasma
  • Perricone MD no makeup foundation
  • Perricone MD exfoliating pore refiner
  • Perricone MD firming eye cream
  • Perricone MD cold plasma sub d

Some of the best Perricone MD products are; Perricone No Makeup, Vitamin C Brightening Serum, MD Supergreens Supplement Powder, Cold Plasma Neck and Chest Broad Spectrum SPF 25, and Cocoa Moisture Mask.

What are the Ingredients Found in Perricone MD?

Some of the common ingredients used to formulate these products include;

  • Hyaluronic Acid – This ingredient has multiple roles in regulating various biological processes such as skin repairment, wound healing, and tissue regeneration. According to the International Journal of Biological Macromolecules.
  • Vitamin F – this is unsaturated fat like omega 3, 6, and 9. Its sources include; sardines, chia seed oil, flaxseed oil, pumpkin seed oil and, macadamia seed oil. Vitamin F works to maintain the water permeability barrier of the skin according to the International Journal of Molecular Sciences. This helps prevent skin conditions such as dermatitis.
  • DMAE – dimethylaminoethanol is a potent anti-inflammatory agent that maintains skin firmness. According to the American Journal of Clinical Dermatology, DMAE also improves the underlying facial muscle tone.
  • Acyl-glutathione – this is a naturally occurring antioxidant which decreases due to age, stress as well as other environmental aggressors. According to Dermatology Reports, glutathione is widely used in skin lightening products owing to its effectiveness. However, this ingredient is known to worsen acne.
  • Vitamin E – this is an important fat-soluble antioxidant that has been in use for decades. It is claimed to protect the skin from harmful solar radiation by acting as a free-radical scavenger according to the Indian Dermatology Online Journal. Vitamin E sources include spinach, nuts, olive oil, sunflower oil, and whole grains.

Is Perricone Any Good?

Perricone products may be considered as good products because they embrace a holistic approach in terms of its ingredients and mechanism of action. Its long-time presence in the market, as well as its committed fan base, could also mean that this product is worth the price tag. The “No Makeup” makeup line is a huge success as consumers with sensitive skin can apply makeup stress-free.

Does Perricone MD work?

Reviews for Perricone MD however few, show that some consumers approved while others critiqued them. For instance, the Cold Plasma + Neck and Chest Broad SPF 25 had lots of positive reviews. Consumers claimed that the results were instant. On the other hand, negative reviewers were not pleased by the filmy feel of the product. Some of them even commented that it was not worth the price tag.

Where Can I Buy Perricone MD Products?

Perricone MD products are sold at major department stores, makeup stores, and online retail stores.

How Much are Perricone MD Products?

Some of the costs of the products include;

  • Growth Factor Firming and Lifting Serum – $129.00
  • Vitamin C Ester Brightening Overnight Treatment – $99.00
  • Cold Plasma Neck and Chest Broad Spectrum SPF – $89.00
  • Hyaluronic Intensive Moisturizer – $69.00
Check the Official Website to Purchase this Product.

What are Alternatives to Perricone MD Products?

There are many organic cosmeceuticals in the market which serve as good alternatives to this line of products. Amala is one such brand. This organic skincare line is impressively dedicated to its clinical trial compliance. For every product Amala formulates, the company claims to conduct third party clinical trials. Another brand of the same caliber is Pai skincare. This line of products is formulated for those with a range of sensitive skin conditions such as rosacea, eczema, and reactive skin.

Final Word on Perricone

Dr. Perricone’s line of skincare products follows a holistic approach which may give it a superior standing compared to other inorganic beauty products. Perricone MD products such as the Perricone no makeup foundation serum, Perricone eye firming cream, or Perricone no makeup lipstick all have positive reviews. And apart from that, some of these products scooped awards from beauty magazines. For instance, the No Makeup Instant Blur Powder received the 2017 O Magazine award.

On the flip side, there are negative reviews for Perricone MD products. Some consumers have denounced the quality of some products such as the DMAE Firming Pads which they claimed was too dry for their liking. Consumers also pointed out the high price tags of the products under this line.

Moreover, some consumers were concerned about what Perricone products are unsafe. Although some of the products contain ingredients that may irritate (such as acyl-glutathione) some sensitive individuals, these products are relatively safe.

Depending on your unique consumer needs, these products may be effective or ineffective. If you are up to the challenge of observing Dr. Perricone’s clean diet as reinforcement to the working of these products, then you should give it a try. If not, there are other organic products like Clinique, Instantly Ageless, and Image Skin Care with better reviews that may be more pocket friendly.

Alternatives you may explore could be Mario Badescu, Obagi skin care, and Arbonne skincare products. Apart from these, there are many more organic products in the market such as Nu Skin Products, Murad Skin Care, Crepe Erase, Mary Kay and Rodan + Fields Skin Care. To settle for the best, go for those with popular skincare ingredients, many positive reviews, suitable for your skin type, and are easy on your pocket.

Where to Buy Perricone MD?

Check the Official Website to Purchase this Product.

Dermspotlight Beauty

Product recommendations, skin care tips, and how-tos, delivered to your inbox.

Your First Review of Perricone MD Awaits

Review this product & share your experiences with other customers. Don't see your question? Ask away!

Average Customer Rating:4.1 / 5.0 
10 Customer Reviews

Rating Snapshot:

Bottom Line: 90% would recommend it to a friend
Reset sorting

    Sharon,  was invited to write this review Learn More

    It works great I recommend this product

    By Sharon 

    Overall Experience:

    The product works great my skin has changed since using this product I recommended this product what a difference it has made.

    Pros and Cons:

    • skin is smoother
    No "cons" were specified in this review.
  1. Flag

    April 19, 2021 7:55 am

    Carolyn Stearns,  was invited to write this review Learn More

    I see improvement and want to continue using.

    By Carolyn Stearns 

    Overall Experience:

    I wanted to improve my facial skin because it seems to be too dry and wrinkly. I have noticed my skin is more hydrated and the finer wrinkles are slowly going away. I have used Dr. Perricone MD for 3 months. I want to continue for another 3 months to see if it improves more. Pleased with Perricone MD products.

    Pros and Cons:

    • hydrated skin
    No "cons" were specified in this review.
  2. Flag

    April 16, 2021 11:17 am

    Rebekah,  was invited to write this review Learn More

    Very impressed with the transformation of my skin already

    By Rebekah 

    Overall Experience:

    I am about to turn 48 and do not ever want to feel out look my age. My skin feels and looks tighter and brighter.

    Pros and Cons:

    • Tighter and Brighter skin
    No "cons" were specified in this review.
  3. Flag

    April 13, 2021 4:33 am

    Julie,  was invited to write this review Learn More

    Love how my skin feels! So smooth and soft!

    By Julie 

    Overall Experience:

    I have definitely seen improvement in the look of my skin. The wrinkle areas I was obsessing over before are much smoother and tighter. An unexpected result was how my skin feels. My face feels so smooth and soft and is actually less sensitive than it used to be.

    Pros and Cons:

    • My complexion is glowing!
    No "cons" were specified in this review.
  4. Flag

    April 12, 2021 7:02 am

    Grace Gate,  was invited to write this review Learn More

    Cold Plasma Ingredients amount?

    By Grace Gate 

    Overall Experience:

    What is the percentage of DMAE in the Cold Plasma? Is it pure DMAE or DMAE BITRATE? I would like to know, before I make a purchase! Thank you.

    Pros and Cons:

    No "pros" were specified in this review.
  5. No "cons" were specified in this review.
  6. Flag

    March 31, 2021 7:38 am

    Pat,  was invited to write this review Learn More

    Don't Buy! Horrible reaction!

    By Pat 

    Length of Use: Less than 3 months

    Overall Experience:

    If you use it, use it up fast. Because I stopped using it for a while and went back and had a horrible reaction. I just started using new meds, so I thought it was that. A month or so later I used Perricone again. Oh boy! What a disaster. My eyes were almost shut, my face was swollen and I had blisters everywhere. Where the cream touched my hands also broke out. I looked at the reviews and there are HUNDREDS of negative reviews. I can’t imagine how these products are still allowed to be sold. I never had a reaction like this to any product before.

    Pros and Cons:

    • Nothing
    • $$$$$$ Horrible reaction

    Which products did you end up using?

    Anything but Perricone


    January 21, 2021 3:42 pm

    Donna Floyd,  was invited to write this review Learn More

    Good Product and hoping it will work

    By Donna Floyd 

    Overall Experience:

    I am 61 and trying to keep my skin looking good. I feel like using this product will help me with this goal.

    Pros and Cons:

    • skin looking good
    No "cons" were specified in this review.
  7. Flag

    October 12, 2020 9:28 am

    Cindy,  was invited to write this review Learn More

    Dr. Perricone MD high quality natural products

    By Cindy 

    Overall Experience:

    I’m not sure I am seeing strong positive changes, but I do know that there are no negatives! And that is something when using high quality natural products. I will evaluate again at the end of my first 6 months of using the complex. Thank you for a great product!

    Pros and Cons:

    No "pros" were specified in this review.
  8. No "cons" were specified in this review.
  9. Flag

    September 28, 2020 12:58 pm

    Laura jordan,  was invited to write this review Learn More

    Something new and refreshing and awesome

    By Laura jordan 

    Overall Experience:

    My skin feels Smother in the morning, not dry anymore, since I started taking Perricone MD the elasticity of my sling is fabulous and I’m 55 years old woman and I look much younger thank you Dr. Perricone.

    Pros and Cons:

    • skin feels smother
    No "cons" were specified in this review.
  10. Flag

    September 21, 2020 12:29 pm

    RoseMarie Odom,  was invited to write this review Learn More

    Perricone MD Skin Care Products Review

    By RoseMarie Odom 

    Overall Experience:

    I have enjoyed taking this product and have seen results! I started to take the product in an attempt to help correct the dark circles under my eyes, which I believe started when I had insomnia for at least 4–6 months while going through Menopause. :(. I also have the dreaded ’11’ lines in between my eyebrows. I have noticed some improvement after using the product for the past few weeks! I hope to see even better results as I continue to take the product.

    Pros and Cons:

    • Its working on my dark circles under the eyes
    No "cons" were specified in this review.
  11. Flag

    September 15, 2020 12:48 pm


Add a YouTube video